NEUROPSYCHOLOGICAL AND QUALITY OF LIFE OUTCOMES IN PKU PATIENTS: EXPERT RECOMMENDATIONS OF ASSESSMENT TOOLS IN BRAZIL

Neuropsychological and quality of life outcomes in PKU patients: expert recommendations of assessment tools in Brazil

Background Phenylketonuria (PKU) is an inborn error of metabolism caused by deficient activity of phenylalanine hydroxylase.In Brazil, the National Neonatal Screening Program enables early treatment of patients with PKU, which prevents them from developing severe neurological damage and mental disabilities.However, here between 20 and 30% of early-

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The oral bioavailability, excretion and cytochrome P450 inhibition properties of epiberberine: an in vivo and in vitro evaluation

Ning Chen,1 Xiao-yan Yang,1,2 Chang-e Guo,1 Xin-ning read more Bi,1 Jian-hua Chen,1 Hong-ying Chen,1 Hong-pin Li,1 Hong-ying Lin,1 Yu-jie Zhang1 1School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 2Nanjing Sanhome Pharmaceutical Co., Ltd., Nanjing, China Abstract: Epiberberine (EPI) is a novel and potentially effecti

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Introduction of day case hip and knee replacement programme at an inpatient ward is safe and may expedite shortening of hospital stays of traditional arthroplasties

Abstract Purpose We investigated the safety of primary hip and knee replacements with same day discharge (SDD) and their effect on length of stay (LOS) of traditional inpatient arthroplasties at our elective orthopaedic ward.Methods 200 patients underwent elective, unilateral primary day case total hip (THA, n = 94), total knee (TKA, n = 60) and un

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The role of nutrient availability and resorption efficiency and their impact on nutrient conservation in mangroves

BACKGROUND AND OBJECTIVES: Nutrient availability influences mangrove forest structure and productivity.The conversion of mangroves into aquaculture ponds can lead to significant disturbances, resulting in long-term consequences associated with the clearing of vegetation and changes in the physico-chemical properties of the soil.These alterations ma

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